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. 2019 Jul 25;63(8):e00758-19.
doi: 10.1128/AAC.00758-19. Print 2019 Aug.

Repeated Detection of Carbapenemase-Producing Escherichia coli in Gulls Inhabiting Alaska

Christina A Ahlstrom  1 , Andrew M Ramey  2 , Hanna Woksepp  3 , Jonas Bonnedahl  4   5
Affiliations

Repeated Detection of Carbapenemase-Producing Escherichia coli in Gulls Inhabiting Alaska

Christina A Ahlstrom et al. Antimicrob Agents Chemother. .

Abstract

Here, we report the first detection of carbapenemase-producing Escherichia coli in Alaska and in wildlife in the United States. Wild bird (gull) feces sampled at three locations in Southcentral Alaska yielded isolates that harbored plasmid-encoded blaKPC-2 or chromosomally encoded blaOXA-48 and genes associated with antimicrobial resistance to up to eight antibiotic classes.

Keywords: carbapenemase-producing Enterobacteriaceae; multidrug resistance; whole-genome sequencing; wild birds.

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Figures

FIG 1
FIG 1
Maximum likelihood phylogenetic tree of carbapenem-resistant Escherichia coli core genome single nucleotide polymorphisms. Isolates originated from gull fecal samples collected June and August 2016 at three locations in Alaska, as indicated by shaded circles, namely, Anchorage mudflats (A), Soldotna landfill (S), and Kasilof River (K). Presence of antimicrobial resistant genes detected in silico is indicated in the matrix to the right, with colors representing different antibiotic classes to which resistance is associated. Asterisks (*) indicate carbapenemase genes.
See this image and copyright information in PMC

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