Stick it to E3s

Affiliations

¹ CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
² CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. gwinter@cemm.oeaw.ac.at.

Comment

Matthias Brand et al. Nat Chem Biol. 2019 Jul.

. 2019 Jul;15(7):655-656.

doi: 10.1038/s41589-019-0312-8.

¹ CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
² CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. gwinter@cemm.oeaw.ac.at.

No abstract available

Comment on

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16.
Zhang X, Crowley VM, Wucherpfennig TG, Dix MM, Cravatt BF. Zhang X, et al. Nat Chem Biol. 2019 Jul;15(7):737-746. doi: 10.1038/s41589-019-0279-5. Epub 2019 Jun 17. Nat Chem Biol. 2019. PMID: 31209349 Free PMC article.
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK. Spradlin JN, et al. Nat Chem Biol. 2019 Jul;15(7):747-755. doi: 10.1038/s41589-019-0304-8. Epub 2019 Jun 17. Nat Chem Biol. 2019. PMID: 31209351 Free PMC article.