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. 2019 Oct;19(10):747-751.
doi: 10.1089/vbz.2018.2324. Epub 2019 Jun 18.

Dengue Virus in Bats from Córdoba and Sucre, Colombia

Alfonso Calderón  1   2 , Camilo Guzmán  1   2 , Salim Mattar  1 , Virginia Rodriguez  3 , Caty Martínez  1 , Lina Violet  1 , Jairo Martínez  1 , Luiz Tadeu Moraes Figueiredo  4
Affiliations

Dengue Virus in Bats from Córdoba and Sucre, Colombia

Alfonso Calderón et al. Vector Borne Zoonotic Dis. 2019 Oct.

Abstract

Natural infection of dengue virus (DENV) in bats is an unexplored field in Colombia. To detect the presence of DENV in bats, a descriptive prospective study using a nonprobabilistic sampling was carried out; 286 bats in 12 sites were caught. Sample tissues of different animals were obtained; the RNA was obtained from tissues and a nested-RT-PCR was carried out and detected amplicons of 143 fragment of the NS5 gene were sequenced by the Sanger method. In nonhematophagous bats Carollia perspicillata and Phyllostomus discolor captured in Ayapel and San Carlos (Córdoba), respectively, an amplicon corresponding to NS5 was detected. The amplicons showed a high similarity with serotype-2 dengue virus (DENV-2). This is the first evidence of the DENV-2 genome in bats in from the Colombian Caribbean.

Keywords: Chiroptera; flavivirus; host; infection; zoonoses.

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Conflict of interest statement

No competing financial interests exist.

Figures

<b>FIG. 1.</b>
FIG. 1.
Capture sites of bats in Córdoba and Sucre (Colombia).
<b>FIG. 2.</b>
FIG. 2.
Phylogenetic tree by ML method; four clades are shown and the obtained sequences from Cordoba and Sucre bats are shown with additional circles. ML, maximum likelihood.
See this image and copyright information in PMC

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