Sleep: DNA Repair Function for Better Neuronal Aging?
- PMID: 31211981
- DOI: 10.1016/j.cub.2019.05.018
Sleep: DNA Repair Function for Better Neuronal Aging?
Abstract
A novel potential role of sleep is neuronal DNA repair. Live imaging of chromosome dynamics in zebrafish neurons has uncovered how sleep can repair DNA breaks accumulated during wake to maintain genome integrity and likely slow down neuronal aging.
Copyright © 2019 Elsevier Ltd. All rights reserved.
Comment on
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Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons.Nat Commun. 2019 Mar 5;10(1):895. doi: 10.1038/s41467-019-08806-w. Nat Commun. 2019. PMID: 30837464 Free PMC article.
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