Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Aug 13;48(3):286-289.
doi: 10.1016/j.rboe.2012.05.009. eCollection 2013 May-Jun.

Brittle bone disease: A case report

Affiliations
Review

Brittle bone disease: A case report

Rodrigo Pace Lasmar et al. Rev Bras Ortop. .

Abstract

We report a case of a female patient, 27 years old, with several episodes of fractures after low energy trauma and the first documented episode only to 18 years of age. Extensive research has not found the exact etiology of the disease. The orthopedic monitoring has targeted prevention and treatment of fractures.

Keywords: Osteogenesis imperfect Ehlers-Danlos syndrome Metabolic Bone diseases.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Oblique view x-rays of the left foot; AP and oblique view of the right foot showing fractures in different stages of consolidation, with no history of major trauma or previous complaint of pain.
Fig. 2
Fig. 2
AP view x-ray of coxofemoral joint; the arrows show signs of stress fractures of the femoral neck.
Fig. 3
Fig. 3
Sign of new stress fracture in the left femur neck, despite preventive fixation two years prior to the complaint of hip pain.
Fig. 4
Fig. 4
AP view x-ray of the left coxofemoral joint showing fracture healing after conservative treatment.

References

    1. Whyte M.P. In: Favus MJ. Primer on the metabolic bone diseases and disorders of mineral metabolism. 4th ed. Williams & Wilkins; Philadelphia: Lippincott: 1999. Osteogenesis imperfecta. 386-9.
    1. Rauch F., Glorieux F.H. Osteogenesis imperfecta. Lancet. 2004;363(9418):1377–1385. - PubMed
    1. Byers P.H., Wallis G.A., Willing M.C. Osteogenesis imperfecta: translation of mutation to phenotype. J Med Genet. 1999;28(7):433–442. - PMC - PubMed
    1. Kim C.A., Gonzalez C.H. Osteogenese imperfeita: revisao. Pediatria (São Paulo) 1993;15(1):8–21.
    1. Pyertz R.E., Levin L.S. Aortic root dilatation and valvular dysfuntion in Osteogenesis imperfecta. Circulation. 1981;64:1193A.

LinkOut - more resources