[CAPSUMEN IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME]

Abstract

Irritable bowel syndrome (IBS) is a common functional intestinal disorder, the frequency of which varies from 5% to 20% in the population depending on the geographical region and the criteria used for diagnosis. Aim of the study - to compare the clinical course of the IBS symptoms in patients receiving and not receiving capsumen. A cross-sectional study was conducted and it included adult patients with IBS. The study included 112 patients with IBS with diarrhea and constipation, which amounted to 4 groups: 1st group - 35 patients with IBS with diarrhea, who was managed in treatment with capsumen, 2nd group - 21 patients with IBS with diarrhea, who does not received capsumen, 3rd group - 34 patients with IBS with constipation, who received capsumen, 4th group - 22 patients with IBS with constipation, who does not received capsumen. Capsumen statistically significantly contributed to the reduction (disappearance) of abdominal pain in IBS patients with diarrhea and constipation already on the 2nd week of treatment. When capsumen was used the fastest positive dynamics in the reduction (disappearance) of meteorism was observed. Capsumen helps to relieve diarrhea and constipation on the 2nd week of treatment. Capsumen contributes to the normalization of intestinal microflora (growth of the obligate flora, reduction of conditionally-pathogenic, normalization of the indicator F/B). Capsumen application helps to improve the quality of life of patients with IBS, reducing the frequency of anxiety and depression.