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. 2019 Oct;46(10):952-990.
doi: 10.1111/joor.12842. Epub 2019 Jul 12.

Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis

Carlos Miguel Marto  1   2   3   4 , Anabela Baptista Paula  1   2   3 , Tiago Nunes  1 , Miguel Pimenta  1 , Ana Margarida Abrantes  2   3   5 , Ana Salomé Pires  2   3   5 , Mafalda Laranjo  2   3   5 , Ana Coelho  1   2   3 , Helena Donato  6 , Maria Filomena Botelho  2   3   5 , Manuel Marques Ferreira  2   3   7 , Eunice Carrilho  1   2   3
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Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis

Carlos Miguel Marto et al. J Oral Rehabil. 2019 Oct.

Abstract

Objectives: To compare the treatments used to treat dentin hypersensitivity (DH), based on its efficacy and effect duration.

Methods: Medline/PubMed, Cochrane Library, EMBASE and ClinicalTrials were searched for articles published between 1 January 2008 and 14 November 2018, in English, Portuguese or Spanish, reporting clinical trials, completed and with results. This systematic review protocol was registered in PROSPERO, number CRD42019121986.

Results: Seventy-four randomised clinical trials were included in the systematic review, reporting patients from 16 to 65 years old, with a clinical diagnosis of DH, that evaluate the efficacy of a desensitising product, compared to pre-treatment, used the evaporative method stimulation and the visual analogue scale. These studies evaluated 5366 patients and at least 9167 teeth. Seven follow-up periods were considered corresponding to an immediate, medium or long-time effect. Sixty-six studies were included in the quantitative synthesis. Glutaraldehyde with HEMA, glass ionomer cements and Laser present significant immediate (until 7 days) DH reduction. Medium-term (until 1 month) reduction was observed in stannous fluoride, glutaraldehyde with HEMA, hydroxyapatite, glass ionomer cements and Laser groups. Finally, long-term significant reduction was seen at potassium nitrate, arginine, glutaraldehyde with HEMA, hydroxyapatite, adhesive systems, glass ionomer cements and LASER.

Conclusions: All active ingredients show efficacy in DH reduction in different follow-up times. Only in-office treatments are effective in immediate DH reduction, maintaining its efficacy over time. For long-time effects, at-home treatments can also be used. More standardised evaluation protocols should be implemented to increase the robustly of the results.

Keywords: dentin desensitising agent; dentin hypersensitivity; dentin hypersensitivity treatments; dentin sensitivity; evidence-based dentistry; systematic review.

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References

REFERENCES

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