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Comment
. 2019 Jun;570(7761):E34-E42.
doi: 10.1038/s41586-019-1296-y. Epub 2019 Jun 19.

Mitochondrial fission requires DRP1 but not dynamins

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Comment

Mitochondrial fission requires DRP1 but not dynamins

Tiago Branco Fonseca et al. Nature. 2019 Jun.
No abstract available

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References

    1. Bleazard, W. et al. The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat. Cell Biol. 1, 298–304 (1999). - DOI
    1. Cereghetti, G. M. et al. Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria. Proc. Natl Acad. Sci. USA 105, 15803–15808 (2008). - DOI
    1. Kalia, R. et al. Structural basis of mitochondrial receptor binding and constriction by DRP1. Nature 558, 401–405 (2018). - DOI
    1. Ji, W. K., Hatch, A. L., Merrill, R. A., Strack, S. & Higgs, H. N. Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites. eLife 4, e11553 (2015). - DOI
    1. Lee, J. E., Westrate, L. M., Wu, H., Page, C. & Voeltz, G. K. Multiple dynamin family members collaborate to drive mitochondrial division. Nature 540, 139–143 (2016). - DOI

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