Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Jun 19;102(6):1089-1091.
doi: 10.1016/j.neuron.2019.05.052.

Mitochondrial Function in 22q11 Deletion Syndrome

Emily B Warren  1 , Eric M Morrow  2
Affiliations
Free article
Comment

Mitochondrial Function in 22q11 Deletion Syndrome

Emily B Warren et al. Neuron. .
Free article

Abstract

Copy number variant disorders arise from altering the dosage of multiple contiguous genes. In this issue of Neuron, Fernandez et al. (2019) identify haploinsufficiency of mitochondrial Txnrd2 as an important contributor to the hypo-cortico-cortical connectivity of 22q11 deletion syndrome.

Keywords: 22q11 deletion; CNV; ROS; Txnrd2; copy number variant; cortico-cortical connectivity; mitochondria; reactive oxygen species.

PubMed Disclaimer

Comment on

LinkOut - more resources