Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2020 Apr;73(2):129-136.
doi: 10.4097/kja.d.18.00275. Epub 2019 Jun 21.

Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital

Se Hee Na  1   2 , Cheung Soo Shin  1   2 , Gwan Ho Kim  1 , Jae Hoon Kim  1 , Jong Seok Lee  1   2
Affiliations
Observational Study

Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital

Se Hee Na et al. Korean J Anesthesiol. 2020 Apr.

Abstract

Background: The long-term outcomes of patients discharged from the hospital after successful care in intensive care unit (ICU) are not briskly evaluated in Korea. The aim of this study was to assess long-term mortality of patients treated in the ICU and discharged alive from the hospital and to identify predictive factors of mortality.

Methods: In 3,679 adult patients discharged alive from the hospital after ICU care between 2006 and 2011, the 1-year mortality rate (primary outcome measure) was investigated. Various factors were entered into multivariate analysis to identify independent factors of 1-year mortality, including sex, age, severity of illness (APACHE II score), mechanical ventilation, malignancy, readmission, type of admission (emergency, elective surgery, and medical), and diagnostic category (trauma and non-trauma).

Results: The 1-year mortality rate was 13.4%. Risk factors that were associated with 1-year mortality included age (hazard ratio: 1.03 [95% CI, 1.02-1.04], P < 0.001), APACHE II score (1.03 [1.01-1.04], P < 0.001), mechanical ventilation (1.96 [1.60-2.41], P < 0.001), malignancy (2.31 [1.82-2.94], P < 0.001), readmission (1.65 [1.31-2.07], P < 0.001), emergency surgery (1.66 [1.18-2.34], P = 0.003), ICU admission due to medical causes (4.66 [3.68-5.91], P < 0.001), and non-traumatic diagnostic category (6.04 [1.50-24.38], P = 0.012).

Conclusions: The 1-year mortality rate was 13.4%. Old age, high APACHE II score, mechanical ventilation, malignancy, readmission, emergency surgery, ICU admission due to medical causes, and non-traumatic diagnostic category except metabolic/endocrinologic category were associated with 1-year mortality.

Keywords: Critical care outcomes; Intensive care unit; Long-term outcomes; Mortality; Risk factors; Survival analysis.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1.
Fig. 1.
Flow diagram of patient screening for this study. The schematic shows the inclusion criteria for patients admitted to the ICU from 2006 to 2011. DNR: do not resuscitation, ICU: intensive care unit.
Fig. 2.
Fig. 2.
Cox’s regression analysis curves showing 1-year mortality after hospital discharge of the total post-ICU patients and subgroups based on the type of admission. ICU: intensive care unit. *Emergency surgical patients have a higher mortality compared with elective surgical patients (P = 0.003). †Medical patients have a higher mortality compared with elective surgical patients (P < 0.001).
See this image and copyright information in PMC

Comment in

References

    1. Health Insurance Review Agency . Seoul: ICU benefits appropriateness evaluation report. HIRA e-Book [Internet] 2004 Dec [cited 2018 Sep 17]. Available from: https://www.hira.or.kr/sViewer/index.do?ebookSn=418.
    1. Angus DC, Carlet J, Brussels Roundtable P. Surviving intensive care: a report from the 2002 Brussels roundtable. Intensive Care Med. 2003;29:368–77. - PubMed
    1. Dowdy DW, Needham DM, Mendez-Tellez PA, Herridge MS, Pronovost PJ. Studying outcomes of intensive care unit survivors: the role of the cohort study. Intensive Care Med. 2005;31:914–21. - PubMed
    1. Jackson JC, Pandharipande PP, Girard TD, Brummel NE, Thompson JL, Hughes CG, et al. Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the brain-ICU study: a longitudinal cohort study. Lancet Respir Med. 2014;2:369–79. - PMC - PubMed
    1. Norman BC, Jackson JC, Graves JA, Girard TD, Pandharipande PP, Brummel NE, et al. Employment outcomes after critical illness: an analysis of the bringing to light the risk factors and incidence of neuropsychological dysfunction in ICU survivors cohort. Crit Care Med. 2016;44:2003–9. - PMC - PubMed

Publication types