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. 2019 Jun;14(2):51-56.
doi: 10.1016/j.joto.2019.01.004. Epub 2019 Jan 30.

The cardiovascular aspects of a Ménière's disease population - A pilot study

Ângela Reis Rego  1 , David Dias  1 , Ana Pinto  1 , Sandra Sousa E Castro  1 , Telma Feliciano  1 , Cecília Almeida E Sousa  1
Affiliations

The cardiovascular aspects of a Ménière's disease population - A pilot study

Ângela Reis Rego et al. J Otol. 2019 Jun.

Erratum in

Abstract

Introduction: MD is considered a rare disease. An adequate model that explains MD's pathophysiology is not well established. Recently, the vascular theory of the disease has been revived.

Objectives: To characterize a MD population according to its cardiovascular risk and correlate it to the MD clinical course.

Methods: In this retrospective chart study the data of 31 MD patients observed between January 2017 and April 2018 in a tertiary university hospital were reviewed. Patients included in the study were diagnosed according to the Bárány Society criteria. Lost follow-ups, patients with autoimmune disease, atopy or allergy, major psychiatric disease and migraine were excluded. Age, gender, cardiovascular risk factors, audiometric and vestibular parameters, occurrence of MD attacks in the previous 6 months, vestibular medication in course and time course of MD were recorded and compared between groups (with and without cardiovascular risk factors).

Results: 31 patients (61.3% females) mean aged 60.3 years (±9.7) were studied. 74% of the population had at least one risk factor and 51.6% of patients had attacks in the last 6 months. There was a statistically significant difference in the occurrence of MD attacks in the last 6 months (p = 0.014) between MD patients with and without risk factors. Mean PTA thresholds were higher and speech discrimination was lower in individuals with more cardiovascular risk factors.

Conclusions: Treatment of MD focusing on vascular risk factors may allow a better control of symptoms and result in a decreased need for ablative procedures in this disorder.

Keywords: Cardiovascular disease; Hypertension; Ménière disease; Prognosis.

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Figures

Graphic1
Graphic1
Stratified population according to age (years).
Graphic 2
Graphic 2
Prevalence of CVRFs among the population (number of risk factors).
Graphic 3
Graphic 3
Treatment in course.
See this image and copyright information in PMC

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