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. 1979 Mar;36(3):519-25.

Failure to block lymphocyte Fc receptor with anti-B lymphocyte sera (anti-DRW) in man

J P Soulillou, M A Peyrat

Failure to block lymphocyte Fc receptor with anti-B lymphocyte sera (anti-DRW) in man

J P Soulillou et al. Immunology. 1979 Mar.

Abstract

Sera harvested from multiparous women or from allograft recipients who had rejected their kidneys and containing various anti-DRW specificities, were studied on peripheral blood or lymph-node lymphocytes bearing or lacking the relevant B-cell alloantigen, for their EA or EAC-rosette-inhibition activity. Inhibition of C3 or Fc-receptor occurred independently of their anti-B lymphocyte cytotoxicity pattern. The same conclusion was reached when lymphocytes were either macrophage depleted or B-lymphocyte enriched. These results do not suggest a relationship in man between B-lymphocyte (DRW) alloantigen and Fc or C3 receptor structure.

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