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Comment
. 2019 Jun 20;74(6):1105-1107.
doi: 10.1016/j.molcel.2019.06.004.

Put the Pedal to the METTL1: Adding Internal m7G Increases mRNA Translation Efficiency and Augments miRNA Processing

Konstantinos Boulias  1 , Eric Lieberman Greer  2
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Put the Pedal to the METTL1: Adding Internal m7G Increases mRNA Translation Efficiency and Augments miRNA Processing

Konstantinos Boulias et al. Mol Cell. .
Free article

Abstract

Complementary papers by Zhang, Liu, and colleagues (Zhang et al., 2019) and Pandolfini, Barbieri, and colleagues (Pandolfini et al., 2019) develop new sequencing techniques that reveal that METTL1 N7-methylates internal guanosines in mRNAs and miRNAs to increase translation efficiency and miRNA processing, respectively.

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