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Comment
. 2019 Jun 21;294(25):9689.
doi: 10.1074/jbc.L119.009476.

On "Isomerization as the secret Achilles' heel of long-lived proteins"

Allen Taylor  1
Affiliations
Comment

On "Isomerization as the secret Achilles' heel of long-lived proteins"

Allen Taylor. J Biol Chem. .
No abstract available

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Conflict of interest statement

The author declares that he has no conflicts of interest with the contents of this article.

Comment on

References

    1. Guseman A. J., and Gronenborn A. M. (2019) Isomerization as the secret Achilles' heel of long-lived proteins. J. Biol. Chem. 294, 7556–7557 10.1074/jbc.H119.008716 - DOI - PMC - PubMed
    1. Lyon Y. A., Collier M. P., Riggs D. L., Degiacomi M. T., Benesch J. L. P., and Julian R. R. (2019) Structural and functional consequences of age-related isomerization in α-crystallins. J. Biol. Chem. 294, 7546–7555 10.1074/jbc.RA118.007052 - DOI - PMC - PubMed
    1. Groenen P. J., van Dongen M. J., Voorter C. E., Bloemendal H., and de Jong W. W. (1993) Age-dependent deamidation of alpha B-crystallin. FEBS Lett. 322, 69–72 10.1016/0014-5793(93)81113-E - DOI - PubMed
    1. Voorter C. E., de Haard-Hoekman W. A., van den Oetelaar P. J., Bloemendal H., and de Jong W. W. (1988) Spontaneous peptide bond cleavage in aging α-crystallin through a succinimide intermediate. J. Biol. Chem. 263, 19020–19023 - PubMed

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