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Comment
. 2019 Jul;96(1):16-19.
doi: 10.1016/j.kint.2019.02.036.

Recognizing diversity in parietal epithelial cells

Vivette D D'Agati  1 , Stuart J Shankland  2
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Recognizing diversity in parietal epithelial cells

Vivette D D'Agati et al. Kidney Int. 2019 Jul.
Free article

Abstract

Parietal epithelial cells comprise a heterogeneous cell population lining Bowman's capsule. The study by Kuppe et al. focused on the peritubular region of Bowman's capsule and explored the cell biology of 2 poorly characterized subtypes-the intermediate and the cuboidal parietal epithelial cells. The early and exuberant proliferative response of these subgroups in murine focal segmental glomerulosclerosis (FSGS) and human glomerular tip lesions identified a novel hot spot for glomerular lesion formation.

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