Conflict of interest: These arrangements have been reviewed and approved by Johns Hopkins University (JHU) in accordance with its conflict of interest policies. PAC serves as an investigator and receives funding from REGENXBIO; serves on the advisory board of, serves as an investigator for, and receives funding and honoraria (through JHU) from Aerpio; serves as an investigator for and receives funding from Alimera Sciences; serves on the advisory board of, serves as an investigator for, has equity in, and receives funding from Allegro Ophthalmics; serves as a consultant for and receives honoraria and funding from Allergan; serves on the advisory board of and receives honoraria from AGTC; serves as a consultant for and receives honoraria and funding from Asclepix; serves as a consultant for and receives honoraria from Astellas; serves as an investigator for and receives funding from Clearside Biomedical; serves on the advisory board of and receives honoraria from Exonate; serves on the advisory board of, acts as an investigator for, and receives funding and honoraria (through JHU) from Genentech/Roche; serves as an investigator for and receives funding from Sanofi Genzyme; is a cofounder of, serves as a consultant for, has equity in, and receives honoraria and funding from Graybug Vision; serves on the advisory board of and receives honoraria from Merck; serves as a consultant for and receives honoraria from Novartis; serves as an investigator for and receives funding from Oxford Biomedica; serves as an investigator for and receives funding from Regeneron; and serves as a consultant and investigator for and receives funding and honoraria from Phio Pharmaceuticals.