Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Dec 25;53(Suppl 1):S138-S150.
doi: 10.5152/TurkPediatriArs.2018.01814. eCollection 2018.

Turkish Neonatal Society guideline on prevention and management of bronchopulmonary dysplasia

Saadet Arsan  1 , Ayşe Korkmaz  2 , Suna Oğuz  3
Affiliations

Turkish Neonatal Society guideline on prevention and management of bronchopulmonary dysplasia

Saadet Arsan et al. Turk Pediatri Ars. .

Abstract
in English, Turkish

Scientific and technological advances in perinatology and neonatology have led to an increased rate of survival and decreased incidences of various neonatal morbidities. However, the incidence of bronchopulmonary dysplasia has remained almost the same for years in very-low-birth-weight preterm infants. Although bronchopulmonary dysplasia is the leading cause of chronic respiratory morbidity in small preterms, no substantial improvement has been achieved in prevention and treatment strategies to date. Currently, postnatal very-low-dose corticosteroids, caffeine, and vitamin A seem to be the drugs of choice, and stem cell therapy appears to be the most promising treatment modality for the future. In this guideline, which was prepared by the Turkish Neonatal Society, recent evidence-based recommendations for the prevention and treatment of bronchopulmonary dysplasia are summarized.

Neonatoloji ve perinatoloji alanındaki bilimsel ve teknolojik gelişmeler çok düşük doğum ağırlıklı prematüre bebeklerde sağkalımı arttırmış ve birçok yenidoğan hastalığının sıklığını azaltmış olmasına rağmen bronkopulmoner displazi sıklığında önemli bir değişme olmamıştır. Bronkopulmoner displazi günümüzde prematüre bebeklerde görülen en önemli kronik solunumsal morbiditedir ve ne yazık ki son 20 yılda korunma ve tedavi yaklaşımlarında önemli bir gelişme olmamıştır. Günümüzde bronkopulmoner displazi korunma ve tedavisinde doğum sonrası çok düşük doz yeni steroid ilaç tedavileri, kafein ve vitamin A ön planda olmakla birlikte gelecekte kök hücre tedavileri önem kazanacak gibi görünmektedir. Türk Neonatoloji Derneği tarafından hazırlanan bu rehber ile ülkemizde yenidoğan sağlığı ile uğraşan hekimlerin bronkopulmoner displazi konusunda güncel ve kanıta dayalı bilimsel veriler eşliğinde, standart tanı, korunma ve tedavi yaklaşımlarında bulunmalarını, etkisiz ya da olumsuz yaklaşımlardan kaçınmalarını sağlamak amaçlanmıştır.

Keywords: Bronchopulmonary dysplasia; guideline; prevention; treatment.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

References

    1. Northway WH, Jr, Rosan RC, Porter DY. Pulmonary disease following respiratory therapy of hyaline-membrane disease: bronchopulmonary dysplasia. N Engl J Med. 1967;276:357–68. - PubMed
    1. Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Care Med. 2001;163:1723–29. - PubMed
    1. Pointdexter BB, Feng R, Schmidt B, et al. Comparisons and limitations of current definitions of bronchopulmonary dysplasia for the prematurity and respiratory outcomes program. Ann Am Thorac Soc. 2015;12:1822–30. - PMC - PubMed
    1. Walsh MC, Wilson-Castello D, Zadell A, et al. Safety, reliability and validity of a physiologic definition of bronchopulmonary dysplasia. J Perinatol. 2003;23:451–56. - PubMed
    1. Isayama T, Lee SK, Yang J, et al. Revisiting the definition of bronchopulmonary dysplasia: effect of changing panoply of respiratory support for preterm neonates. JAMA Pediatr. 2017;171:271–79. - PubMed

LinkOut - more resources