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. 1987 Nov;210(1):153-5.
doi: 10.1007/BF00337772.

Separate DNA sequences are required for normal female and ecdysone-induced male expression of Drosophila melanogaster yolk protein 1

A D Shirras  1 , M Bownes
Affiliations

Separate DNA sequences are required for normal female and ecdysone-induced male expression of Drosophila melanogaster yolk protein 1

A D Shirras et al. Mol Gen Genet. 1987 Nov.

Abstract

Drosophila melanogaster flies were transformed with a yp1-Adh fusion gene with 890 bp of yp1 5' flanking sequence. In an Adh- background these flies show a stage, tissue and sex-specific pattern of alcohol dehydrogenase (ADH) activity characteristic of yolk protein genes. ADH activity is not present in dsxD/dsx pseudomales indicating that this fragment contains sites where the dsx gene product exerts its effect. Transformed male flies do not exhibit ADH activity when injected with 20-hydroxyecdysone while synthesis of native yolk proteins is induced. Thus the hormone inducibility and sex regulation have been separated in this construct.

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References

    1. Dev Biol. 1982 Jan;89(1):225-36 - PubMed
    1. Cell. 1984 Jul;37(3):979-91 - PubMed
    1. Nucleic Acids Res. 1983 Sep 24;11(18):6341-51 - PubMed
    1. Cell. 1986 Jun 20;45(6):859-67 - PubMed
    1. Dev Biol. 1980 Oct;79(2):379-87 - PubMed

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