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Case Reports
. 2018 Jun;8(2):407-415.
doi: 10.1177/1925362118782082. Epub 2018 Jun 6.

A Case of Severe Cardiac Sarcoidosis with Minimal Pulmonary Involvement: A Case Report with Literature Review

Mark R Fowler, Nobby C Mambo
Case Reports

A Case of Severe Cardiac Sarcoidosis with Minimal Pulmonary Involvement: A Case Report with Literature Review

Mark R Fowler et al. Acad Forensic Pathol. 2018 Jun.

Abstract

Sarcoidosis is a granulomatous disease of unknown etiology. Although sarcoidosis is a systemic disease, there appears to be a predilection for involvement of certain organs. The pulmonary system is the most commonly affected system among all racial groups. Cardiac and respiratory complications are the leading causes of death due to sarcoidosis and in certain patient populations about half of these deaths are attributed to cardiac sarcoidosis. There are few autopsy case reports of cardiac sarcoidosis with minimal respiratory involvement making this case report relevant to the importance of the recognition and awareness of this entity. Acad Forensic Pathol. 2018 8(2): 407-415.

Keywords: Autopsy; Cardiac sarcoidosis; Forensic pathology; Noncaseating granuloma; Splenic sarcoidosis.

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Conflict of interest statement

Disclosures & Declaration of Conflicts of Interest: The authors, reviewers, editors, and publication staff do not report any relevant conflicts of interest

Figures

Image 1:
Image 1:
Thickened epicardium with adhesions.
Image 2:
Image 2:
Cross sections of the heart showing replacement of myocardium with tan tissue.
Image 3:
Image 3:
Splenic involvement with many tan nodules.
Image 4:
Image 4:
Noncaseating granulomatous inflammation affecting the myocardium. Note the diffuse interstitial fibrosis with cardiac myocyte loss. Langerhans type giant cells are seen (H&E, x200).
See this image and copyright information in PMC

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