Comparative Study
[Cell-free Pseudomonas vaccine: its immunochemical characteristics and immunogenicity]
[Article in
Russian]
- PMID: 3124416
Item in Clipboard
Comparative Study
[Cell-free Pseudomonas vaccine: its immunochemical characteristics and immunogenicity]
[Article in
Russian]
Zh Mikrobiol Epidemiol Immunobiol.
1987 Nov.
Abstract
Two variants of cell-free protein vaccine have been prepared from the mixture of 4 P. aeruginosa strains, serovars 02, 06, 07 and 011, and from a single P. aeruginosa strain, serovar 02. The preparation contains proteins with molecular weight ranging from 20,000 to 100,000 and the admixture of lipopolysaccharide in negligible amounts (not exceeding 0.08% of dry weight). The vaccine produces no signs of toxicosis in laboratory animals. The vaccine effectively protects mice challenged with P. aeruginosa of different O-serotypes and stimulates the formation of specific protective antibodies in rabbits.
Similar articles
-
Experimental studies on the protective efficacy of a Pseudomonas aeruginosa vaccine.Vaccine. 1989 Dec;7(6):562-6. doi: 10.1016/0264-410x(89)90284-3. Vaccine. 1989. PMID: 2514518
-
[Production and experimental testing of the polyvalency of corpuscular vaccine for the prevention of Pseudomonas aeruginosa infections II. Experimental testing of the immunogenicity of polyvalent corpuscular Pseudomonas aeruginosa vaccine].Zh Mikrobiol Epidemiol Immunobiol. 1981 Oct;(10):74-80. Zh Mikrobiol Epidemiol Immunobiol. 1981. PMID: 6800165 Russian.
-
Vaccines against Pseudomonas aeruginosa infection: 1. Experimental studies.Vaccine. 1985 Jun;3(2):128-36. doi: 10.1016/0264-410x(85)90062-3. Vaccine. 1985. PMID: 3929491
-
Pseudomonas aeruginosa antigens as potential vaccines.FEMS Microbiol Rev. 1997 Nov;21(3):243-77. doi: 10.1111/j.1574-6976.1997.tb00353.x. FEMS Microbiol Rev. 1997. PMID: 9451816 Review.
-
[Pseudomonas aeruginosa preparations for active immunization].Vrach Delo. 1991 Jul;(7):22-7. Vrach Delo. 1991. PMID: 1771827 Review. Russian. No abstract available.