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Review
. 2019 Jun 4:43:75-81.
doi: 10.1016/j.amsu.2019.05.017. eCollection 2019 Jul.

Malignant neoplasms of Meckel's diverticulum; an evidence based review

S A Kabir  1 , S A Raza  2 , S I Kabir  2
Affiliations
Review

Malignant neoplasms of Meckel's diverticulum; an evidence based review

S A Kabir et al. Ann Med Surg (Lond). .

Abstract

An up to date published literature has shown that Meckel's Diverticulum (MD) are discovered incidentally and are benign, malignant transformation is unusual with reported incidence to be only 0.5%-3.2%. The research available on this rare tumour remains scanty, mainly consisting of case reports and case series with many researchers reporting on their own clinical experience and often disagree on not only its epidemiology, but also more so on its surgical indications. In addition to the above there is no agreed standard formal grading and staging classification for primary MD tumour that can not only help assess the tumour in a systematic way, but also advise on a standard treatment plan that is to be followed after emergency surgery. Hence, the aim of this article is to systematically review the latest evidence on these rare types of malignant neoplasm originating from MD, and conclude the best management options when encountered with such situations.

Keywords: Adeno-carcinoma; Carcinoid; Gastro intestinal stromal tumours and rare tumour; Meckel's diverticulum (MD) and malignancy; Neoplasms; Sarcoma; Tumour.

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Figures

Fig. 1
Fig. 1
PRISMA flow diagram.
Fig. 2
Fig. 2
Systematic literature review.
Fig. 3
Fig. 3
Single case reports with indication for surgery: malignancy.
Fig. 4
Fig. 4
Single case reports with indication for surgery: of non-malignant disease.
See this image and copyright information in PMC

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