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Case Reports
. 2019 Jun 27;49(3):168-170.
doi: 10.4274/tjo.galenos.2018.39018.

Breast Carcinoma Metastasis to the Medial Rectus Muscle: Case Report

Özge Yabaş Kızıloğlu  1 , Fatma Paksoy Türköz  2 , Özgün Melike Totuk Gedar  1 , Mert Mestanoğlu  3 , Özlem Yapıcıer  4
Affiliations
Case Reports

Breast Carcinoma Metastasis to the Medial Rectus Muscle: Case Report

Özge Yabaş Kızıloğlu et al. Turk J Ophthalmol. .

Abstract

A 63-year-old woman with metastatic breast carcinoma presented to the ophthalmology clinic with diplopia and right abduction deficit. Magnetic resonance imaging showed isolated enlargement of the right medial rectus muscle. Biopsy of the enlarged muscle revealed metastasis of breast carcinoma. Ocular motility deficit in a patient with breast carcinoma should raise suspicion of metastasis to the orbit involving the extraocular muscles. Orbital imaging and biopsy are necessary for diagnosis and appropriate treatment.

Keywords: Breast carcinoma; extraocular muscle; medial rectus muscle; orbital metastasis.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
Images of the patient at presentation. Abduction of the right eye is limited with retraction of the globe and narrowing of the palpebral fissure
Figure 2
Figure 2
Magnetic resonance imaging of the orbit. Axial postcontrast T1- weighted image showing thickening of the right medial rectus muscle with sparing of the tendon
Figure 3
Figure 3
(A) Hematoxylin-eosin stain. The biopsy specimen of the right medial rectus muscle showing tumor cells (arrows) infiltrating muscle fibers; 400x. (B) Cytokeratin 7 immunohistochemistry of the specimen showing tumor cells (arrows); 400x
See this image and copyright information in PMC

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References

    1. Goldberg RA, Rootman J, Cline RA. Tumors metastatic to the orbit: a changing picture. Surv Ophthalmol. 1990;35:1–24. - PubMed
    1. Shields JA, Shields CL, Brotman HK, Carvalho C, Perez N, Eagle RC Jr. Cancer metastatic to the orbit: the 2000 Robert M. Curts Lecture. Ophthal Plast Reconstr Surg. 2001;17:346–354. - PubMed
    1. Gunalp I, Gunduz K. Metastatic orbital tumors. Jpn J Ophthalmol. 1995;39:65–70. - PubMed
    1. Garrity JA, Henderson JW, Cameron JD. Metastatic carcinomas. In: Henderson’s orbital tumors. 4th ed. New York: Raven Press. 2007:313–326.
    1. Ahmad SM, Esmaeli B. Metastatic tumors of the orbit and ocular adnexa. Curr Opin Ophthalmol. 2007;18:405–413. - PubMed

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