Phosphorylation of actin-binding proteins by casein kinases 1 and 2
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- PMID: 3124847
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Phosphorylation of actin-binding proteins by casein kinases 1 and 2
Biochem Int.
1987 Aug.
Abstract
Filamin and vinculin from chicken gizzards were significantly phosphorylated in vitro by casein kinases 1 and 2, but not by alpha-actinin. Antisera raised against these actin-binding proteins immunoprecipitated the phosphorylated proteins corresponding to filamin and vinculin, but no phosphoprotein corresponding to alpha-actinin was detected. These results suggest that filamin and vinculin are phosphorylated in vivo but alpha-actinin is not.
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