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. 1987 Aug;15(2):321-7.

Phosphorylation of actin-binding proteins by casein kinases 1 and 2

S Nakajo  1 , K Nakaya, Y Nakamura
Affiliations
  • PMID: 3124847

Phosphorylation of actin-binding proteins by casein kinases 1 and 2

S Nakajo et al. Biochem Int. 1987 Aug.

Abstract

Filamin and vinculin from chicken gizzards were significantly phosphorylated in vitro by casein kinases 1 and 2, but not by alpha-actinin. Antisera raised against these actin-binding proteins immunoprecipitated the phosphorylated proteins corresponding to filamin and vinculin, but no phosphoprotein corresponding to alpha-actinin was detected. These results suggest that filamin and vinculin are phosphorylated in vivo but alpha-actinin is not.

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