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Case Reports
. 2019 Nov;49(11):2111-2114.
doi: 10.1002/eji.201848083.

Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza

Michelle M Thomsen  1   2 , Sofie E Jørgensen  1   2 , Merete Storgaard  1 , Lasse S Kristensen  3 , Jakob Gjedsted  4 , Mette Christiansen  5 , Hans Henrik Gad  3 , Rune Hartmann  3 , Trine H Mogensen  1   2   6
Affiliations
Free article
Case Reports

Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza

Michelle M Thomsen et al. Eur J Immunol. 2019 Nov.
Free article
No abstract available

Keywords: IRF3; Influenza; Innate immunity; Interferon; Primary immunodeficiency.

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References

    1. Iwasaki, A. and Pillai, P. S., Nat. Rev. Immunol. 2014. 14: 315-328.
    1. Honda, K. et al., Immunity 2006. 25: 349-360.
    1. Ciancanelli, M. J. et al., Curr. Opin. Immunol. 2016. 38: 109-120.
    1. Garcia-Sastre, A. et al., J. Virol 1998. 72: 8550-8558.
    1. Galani, I. E. et al., Immunity 2017. 46: 875-890.e6.

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