doi: 10.1007/BF01647240.
Selective pressure of antistaphylococcal chemotherapeutics in favour of Pseudomonas aeruginosa in cystic fibrosis
Affiliations
- PMID: 3125114
- DOI: 10.1007/BF01647240
Item in Clipboard
Selective pressure of antistaphylococcal chemotherapeutics in favour of Pseudomonas aeruginosa in cystic fibrosis
Infection.
1987 Nov-Dec.
Abstract
Pseudomonas aeruginosa is insensitive against the majority of oral chemotherapeutics active against staphylococci. During application of such compounds in patients colonized by P. aeruginosa the concentration of P. aeruginosa increased in the majority of treatment episodes by factors between 2.5 and 50000. So, from a microbiological point of view the application of purely antistaphylococcal drugs should not be used prophylactically against staphylococci.
Similar articles
-
Characterization by pyocine typing and serotyping of oral and sputum strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients.Can J Microbiol. 1987 Mar;33(3):221-5. doi: 10.1139/m87-038. Can J Microbiol. 1987. PMID: 3105857
-
Qualitative and quantitative microbiological analysis of sputa of 102 patients with cystic fibrosis.Infection. 1987 Jul-Aug;15(4):270-7. doi: 10.1007/BF01644137. Infection. 1987. PMID: 3117700
-
Quantitative effect of roxithromycin and rifampicin on mucoid cultures from directly plated sputum of cystic fibrosis patients chronically colonized with Pseudomonas aeruginosa.Drugs Exp Clin Res. 1990;16(12):597-605. Drugs Exp Clin Res. 1990. PMID: 2130001
-
Microbiological background for anti-Pseudomonas aeruginosa vaccination in cystic fibrosis.Behring Inst Mitt. 1997 Feb;(98):256-61. Behring Inst Mitt. 1997. PMID: 9382748 Review. No abstract available.
-
Pseudomonas aeruginosa in cystic fibrosis is potentially serious, and more than merely a marker for disease severity.Paediatr Respir Rev. 2015 Oct;16 Suppl 1:35-6. doi: 10.1016/j.prrv.2015.07.016. Epub 2015 Sep 26. Paediatr Respir Rev. 2015. PMID: 26410280 Review. No abstract available.
Cited by
-
Clinical significance of microbial infection and adaptation in cystic fibrosis.Clin Microbiol Rev. 2011 Jan;24(1):29-70. doi: 10.1128/CMR.00036-10. Clin Microbiol Rev. 2011. PMID: 21233507 Free PMC article. Review.
-
Microbiology of airway disease in patients with cystic fibrosis.Clin Microbiol Rev. 1991 Jan;4(1):35-51. doi: 10.1128/CMR.4.1.35. Clin Microbiol Rev. 1991. PMID: 1900735 Free PMC article. Review.
-
Treatment of infections in patients with cystic fibrosis.Infection. 1987;15(5):313-4. doi: 10.1007/BF01647727. Infection. 1987. PMID: 3692601 No abstract available.
-
Lung infections associated with cystic fibrosis.Clin Microbiol Rev. 2002 Apr;15(2):194-222. doi: 10.1128/CMR.15.2.194-222.2002. Clin Microbiol Rev. 2002. PMID: 11932230 Free PMC article. Review.