The role of central 5-hydroxytryptamine in acupuncture analgesia
- PMID: 312529
Item in Clipboard
The role of central 5-hydroxytryptamine in acupuncture analgesia
Sci Sin.
1979 Jan.
Abstract
The role played by central 5-hydroxytryptamine (5-HT) in acupuncture analgesia (AA) has been studied in rats with the tail-flick response as the antinociceptive test. The analgesic effect of acupuncture can be enhanced or lowered by the increment or the decrement of the 5-HT level in the CNS. Furthermore, the turnover rate of 5-HT in the CNS has been found to be greatly facilitated during the period of acupuncture. The results imply that 5-HT in the CNS may be one of the most important neurochemical agents mediating AA.
Similar articles
-
[Autoradiographic visualization on the role of central 3H-5-hydroxytryptamine in acupuncture analgesia].Zhen Ci Yan Jiu. 1990;15(4):269-73. Zhen Ci Yan Jiu. 1990. PMID: 2125891 Chinese.
-
Differential actions of intrathecal naloxone on blocking the tail-flick inhibition induced by intraventricular beta-endorphin and morphine in rats.J Pharmacol Exp Ther. 1985 Jan;232(1):74-9. J Pharmacol Exp Ther. 1985. PMID: 3155550
-
The implication of central serotonin in electro-acupuncture tolerance in the rat.Sci Sin B. 1982 Jun;25(6):620-9. Sci Sin B. 1982. PMID: 6180474
-
[Involvement of serotoninergic systems in analgesia induced by electrical stimulation of brain stem areas (author's transl)].J Physiol (Paris). 1981;77(2-3):473-82. J Physiol (Paris). 1981. PMID: 7026772 Review. French.
-
Serotonin-containing neurons: their possible role in pain and analgesia.Pain. 1977 Oct;4(1):1-21. doi: 10.1016/0304-3959(77)90083-5. Pain. 1977. PMID: 22060 Review.
Cited by
-
Combination of acupuncture and spinal manipulative therapy: management of a 32-year-old patient with chronic tension-type headache and migraine.J Chiropr Med. 2012 Sep;11(3):192-201. doi: 10.1016/j.jcm.2012.02.003. J Chiropr Med. 2012. PMID: 23449932 Free PMC article.
-
Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI.Hum Brain Mapp. 2005 Mar;24(3):193-205. doi: 10.1002/hbm.20081. Hum Brain Mapp. 2005. PMID: 15499576 Free PMC article.
-
Mapping, in the rat central nervous system, of morphine-induced changes in turnover of 5-hydroxytryptamine.J Physiol. 1981 May;314:395-410. doi: 10.1113/jphysiol.1981.sp013715. J Physiol. 1981. PMID: 6171638 Free PMC article.
-
Time-variant fMRI activity in the brainstem and higher structures in response to acupuncture.Neuroimage. 2009 Aug 1;47(1):289-301. doi: 10.1016/j.neuroimage.2009.03.060. Epub 2009 Apr 1. Neuroimage. 2009. PMID: 19345268 Free PMC article.
-
The Involvement of Descending Pain Inhibitory System in Electroacupuncture-Induced Analgesia.Front Integr Neurosci. 2019 Aug 21;13:38. doi: 10.3389/fnint.2019.00038. eCollection 2019. Front Integr Neurosci. 2019. PMID: 31496944 Free PMC article. Review.