T2DM treatment trial results
- PMID: 31253858
- DOI: 10.1038/s41574-019-0234-2
T2DM treatment trial results
Comment on
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Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial.Lancet Diabetes Endocrinol. 2019 Jul;7(7):515-527. doi: 10.1016/S2213-8587(19)30192-5. Epub 2019 Jun 9. Lancet Diabetes Endocrinol. 2019. PMID: 31189517 Clinical Trial.
References
Original article
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- Mosenzon, O. et al. Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial. Lancet Diabetes Endocrinol. https://doi.org/10.1016/S2213-8587(19)30192-5 (2019) - DOI - PubMed
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- Husain, M. et al. Oral semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa1901118 (2019) - DOI - PubMed
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- Pieber, T. R. et al. Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial. Lancet Diabetes Endocrinol. https://doi.org/10.1016/S2213-8587(19)30194-9 (2019) - DOI - PubMed
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- Mosenzon, O. et al. Effects of dapagliflozin on development and progression of kidney disease in patients with type 2 diabetes: an analysis from the DECLARE–TIMI 58 randomised trial. Lancet Diabetes Endocrinol. https://doi.org/10.1016/S2213-8587(19)30180-9 (2019) - DOI - PubMed
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- Gerstein, H. C. et al. Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial. Lancet https://doi.org/10.1016/S0140-6736(19)31149-3 (2019) - DOI - PubMed
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