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. 2019 Jun;58(Suppl 1):1-11.
doi: 10.1007/s00394-019-02027-z.

Nutrition interventions for healthy ageing across the lifespan: a conference report

Affiliations

Nutrition interventions for healthy ageing across the lifespan: a conference report

A Kalache et al. Eur J Nutr. 2019 Jun.

Abstract

Thanks to advances in modern medicine over the past century, the world's population has experienced a marked increase in longevity. However, disparities exist that lead to groups with both shorter lifespan and significantly diminished health, especially in the aged. Unequal access to proper nutrition, healthcare services, and information to make informed health and nutrition decisions all contribute to these concerns. This in turn has hastened the ageing process in some and adversely affected others' ability to age healthfully. Many in developing as well as developed societies are plagued with the dichotomy of simultaneous calorie excess and nutrient inadequacy. This has resulted in mental and physical deterioration, increased non-communicable disease rates, lost productivity and quality of life, and increased medical costs. While adequate nutrition is fundamental to good health, it remains unclear what impact various dietary interventions may have on improving healthspan and quality of life with age. With a rapidly ageing global population, there is an urgent need for innovative approaches to health promotion as individual's age. Successful research, education, and interventions should include the development of both qualitative and quantitative biomarkers and other tools which can measure improvements in physiological integrity throughout life. Data-driven health policy shifts should be aimed at reducing the socio-economic inequalities that lead to premature ageing. A framework for progress has been proposed and published by the World Health Organization in its Global Strategy and Action Plan on Ageing and Health. This symposium focused on the impact of nutrition on this framework, stressing the need to better understand an individual's balance of intrinsic capacity and functional abilities at various life stages, and the impact this balance has on their mental and physical health in the environments they inhabit.

Keywords: Ageing; Bioactives; Biomarkers; Functional ability; Healthspan; Inequalities; Intrinsic capacity; Lifespan; Nutrition; Vitamins.

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Conflict of interest statement

A. Kalache, I. de Hoogh, S.E. Howlett, M. Eggersdorfer, A. Shao and J.C. Griffiths had their travel expenses reimbursed by CRN-I. A. Kalache, I. de Hoogh, A. Shao and D.S. Marsman are employees of their respective companies, International Longevity Centre Global Alliance, TNO, Amway/Nutrilite, and Procter & Gamble Health. B. Kennedy is a board chair of Mt. Tam Pharmaceuticals, a board member and scientific advisor for PDL Pharma, a scientific advisor for Affirmativ Health, and a board member of L-Nutra. M. Eggersdorfer consults for several companies in the field of nutritional ingredients. J.C. Griffiths is an employee of CRN-International. None of the authors declares any conflict of interest in providing their solely scientific opinion for this review.

Figures

Fig. 1
Fig. 1
Visualization of the “profile wheel” resulting from an extensive 360° diagnosis. The profile wheel is constructed of four quadrants: environment, body, behavior and thinking and feeling. The quadrants are further split up in sub-domains, including glucose metabolism, body composition (body), medication use (behavior) and loneliness (environment). The colors represent the traffic light model, with green representing a healthy score for a sub-domain, orange an in-between state and red an unhealthy score
Fig. 2
Fig. 2
Example of a health space, showing the muscle health and wellbeing of an elderly person as compared to a reference group with optimal health and a reference group with compromised health status (no citation, paper under review)
Fig. 3
Fig. 3
Interventions (such as nutrition) and robust public policy are needed to positively affect the functional capacity trajectory as we age (internal ILC figure)

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