Circadian Rhythms: Implications for Health and Disease

Abstract

Circadian rhythms are present in nearly all organisms studied, and are present throughout the human body. The proper coordination of these rhythms, both within the body, and with respect to the environment appears to be important for overall health. This article reviews the available data looking at the association between circadian dysregulation and cardiometabolic, neurologic, and neurodegenerative disease risk. In addition we discuss the limited but growing evidence supporting the use of circadian-based interventions to improve overall health.

Keywords: Aging; Cardiometabolic disease; Circadian; Neurodegeneration.