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Case Reports
. 2019 Nov;66(7):871-873.
doi: 10.1111/zph.12623. Epub 2019 Jul 1.

Crimean-Congo Haemorrhagic Fever: Case study analysis of a sporadic outbreak from Chakwal, Pakistan

Affiliations
Case Reports

Crimean-Congo Haemorrhagic Fever: Case study analysis of a sporadic outbreak from Chakwal, Pakistan

Tahir Yaqub et al. Zoonoses Public Health. 2019 Nov.

Abstract

Crimean-Congo Haemorrhagic Fever (CCHF) is a deadly viral zoonotic disease, which is endemic in Pakistan. We report a case study analysis of three cases of CCHF which occurred in Chakwal, Pakistan in 2016. The disease was suspected in three patients exhibiting clinical symptoms suggestive of CCHF; two of the three patients died. The presence of CCHF was detected by seroconversion (IgG) from the surviving patient, while the antigen was detected in Hyalomma ticks originating from animals in the vicinity. This report indicates increase threat emergence of CCHF in Pakistan and highlights its zoonotic implications requiring immediate interventions under the "One-Health" concept.

Keywords: Chakwal; Crimean-Congo Haemorrhagic Fever; ELISA.

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References

REFERENCES

    1. Abbas, T., Younus, M., & Muhammad, S. A.( 2015). Spatial cluster analysis of human cases of Crimean Congo hemorrhagic fever reported in Pakistan. Infectious Diseases of Poverty, 4, 9. https://doi.org/10.1186/2049-9957-4-9
    1. Athar, M. N., Khalid, M. A. L. I., Ahmad, A. M., Bashir, N., Baqai, H. Z., Ahmad, M., … Bashir, K. (2005). Crimean-congo Hemorrhagic Fever Outbreak in Rawalpindi, Pakistan, February 2002: Contact Tracing and Risk Assessment. American Journal of Tropical Medicine and Hygiene, 72, 471-473.
    1. Begum, F., Wisseman, C. L., & Casals, J. (1970). Tick-borne viruses of West Pakistan. IV. Viruses similar to or identical with, Crimean hemorrhagic fever (Congo-Semunya), Wad Medani and Pak Argas 461 isolated from ticks of the Changa Manga Forest, Lahore District, and of Hunza, Gilgit Agency, W. Pakistan. American Journal of Epidemiology, 92, 197-202. https://doi.org/10.1093/oxfordjournals.aje.a121199
    1. Bodur, H., Akıncı, E., Öngürü, P., Carhan, A., Uyar, Y., Tanrıcı, A., … Kubar, A. (2010). Detection of Crimean-Congo hemorrhagic fever virus genome in saliva and urine. International Journal of Infectious Diseases, 14(3), e247-e249. https://doi.org/10.1016/j.ijid.2009.04.018
    1. Burney, M. I., Ghafoor, A., Saleen, M., Webb, P. A., & Casals, J. (1980). Nosocomial outbrak of viral hemorrhagic fever caused by Crimean Hemorrhagic Fever-Congo virus in Pakistan, January 1976. American Journal of Tropical Medicine and Hygiene, 29, 941-947. https://doi.org/10.4269/ajtmh.1980.29.941

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