Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jun;20(6):e316-e325.
doi: 10.1542/neo.20-6-e316.

Neonatal Hemophagocytic Lymphohistiocytosis

Josef McLean  1 , Roia Katebian  1 , Eugene Suh  1 , Kamran Mirza  2 , Sachin Amin  1
Affiliations
Review

Neonatal Hemophagocytic Lymphohistiocytosis

Josef McLean et al. Neoreviews. 2019 Jun.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is extremely rare in the neonatal period. The incidence of neonatal HLH is not confirmed and may range from 1 in 50,000 to 150,000. The incidence varies based on ethnicity, particularly in populations in which consanguinity is common. HLH is associated with a high fatality rate and poor prognosis, making it important to recognize and diagnose it early. This review will concentrate primarily on the diagnosis and management of neonatal HLH.

PubMed Disclaimer

LinkOut - more resources