Reduced virulence in ciprofloxacin-resistant variants of Pseudomonas aeruginosa strains
- PMID: 3126177
- DOI: 10.1093/jac/20.6.825
Reduced virulence in ciprofloxacin-resistant variants of Pseudomonas aeruginosa strains
Abstract
Pseudomonas aeruginosa strains resistant to ciprofloxacin were obtained from parental strains by serial transfer through subinhibitory concentrations of the drug. They showed reduced virulence for mice, and also increased sensitivity to aminoglycosides.
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