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Clinical Trial
. 1988 Feb;91(1):13-7.

Efficacy of low doses of praziquantel for Schistosoma mansoni and S. haematobium

P Taylor  1 , H M Murare, K Manomano
Affiliations
  • PMID: 3126306
Clinical Trial

Efficacy of low doses of praziquantel for Schistosoma mansoni and S. haematobium

P Taylor et al. J Trop Med Hyg. 1988 Feb.

Abstract

The shortage of available information on the impact of low doses of praziquantel was remedied by a trial of 0, 10, 20, 30 and 40 mg kg-1 against double infections of Schistosoma haematobium and S. mansoni in a rural area of Zimbabwe. No significant differences were found in egg reduction between 20-40 mg kg-1 for S. haematobium and between 30-40 mg kg-1 for S. mansoni. It is suggested that morbidity control can be achieved with lower dosages of praziquantel than currently recommended.

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