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. 2019 Sep;19(9):481-482.
doi: 10.1038/s41568-019-0172-2.

Preclinical rare cancer research to inform clinical trial design

Holly E Barker  1   2 , Clare L Scott  3   4   5   6   7
Affiliations

Preclinical rare cancer research to inform clinical trial design

Holly E Barker et al. Nat Rev Cancer. 2019 Sep.
No abstract available

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References

    1. Gatta, G. et al. Burden and centralised treatment in Europe of rare tumours: results of RARECAREnet-a population-based study. Lancet Oncol. 18, 1022–1039 (2017). - DOI
    1. Sicklick, J. K. et al. Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study. Nat. Med. 25, 744–750 (2019). - DOI
    1. Puca, L. et al. Patient derived organoids to model rare prostate cancer phenotypes. Nat. Commun. 9, 2404 (2018). - DOI
    1. Phan, N. et al. A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids. Commun. Biol. 2, 78 (2019). - DOI
    1. Ray-Coquard, I., Pujade-Lauraine, E. & Ledermann, J. A. New clinical research strategies for rare gynecologic malignancies. Curr. Opin. Obstet. Gynecol. 27, 53–57 (2015). - DOI

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