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. 2020 Sep;30(3):227-234.
doi: 10.1080/08982104.2019.1630642. Epub 2019 Jul 2.

New oral liposomal vitamin C formulation: properties and bioavailability

Maciej Łukawski  1 , Paulina Dałek  1   2 , Tomasz Borowik  2 , Aleksander Foryś  3 , Marek Langner  1   2 , Wojciech Witkiewicz  4 , Magdalena Przybyło  1   2
Affiliations

New oral liposomal vitamin C formulation: properties and bioavailability

Maciej Łukawski et al. J Liposome Res. 2020 Sep.

Abstract

Vitamin C is the exogenous compound necessary for a variety of metabolic processes; therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. In the paper, we present the new liposomal formulation of vitamin C free of harmful organic solvents. The formulation was quantitatively characterized with respect to its chemically composition and nano-structuring. The vitamin C accessibility to cells from the formulation was evaluated using evidence derived from experiments performed on cell cultures. Finally, the enhanced bioavailability of vitamin C from the formulation was demonstrated in the medical experiment.

Keywords: Liposome; bioavailability; efficacy; stability; vitamin C.

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