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. 1988;94(1):21-3.
doi: 10.1007/BF00735874.

Improved recognition memory in monkeys following naloxone administration

T G Aigner  1 , M Mishkin
Affiliations

Improved recognition memory in monkeys following naloxone administration

T G Aigner et al. Psychopharmacology (Berl). 1988.

Abstract

The effects of naloxone on visual recognition were evaluated in five macaques trained in delayed nonmatching-to-sample with trial-unique objects. In four of the five monkeys, naloxone yielded an inverted U-shaped dose-effect curve. For each of these four animals, as well as for all five animals as a group, at least one dose within a narrow range (0.32-3.2 mg/kg) produced a significant increase in the number of objects correctly recognized. Lower doses had little effect, while the highest dose (10.0 mg/kg) tended to disrupt performance.

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References

    1. Lancet. 1981 Nov 14;2(8255):1110 - PubMed
    1. Psychopharmacologia. 1971;20(1):42-7 - PubMed
    1. Psychopharmacology (Berl). 1979 Nov;66(2):199-203 - PubMed
    1. Nature. 1983 Aug 25-31;304(5928):725-7 - PubMed
    1. Ann Neurol. 1984 Mar;15(3):308 - PubMed

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