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Comment
. 2019 Jul 1;50(1):3-4.
doi: 10.1016/j.devcel.2019.06.006.

Repressive Epigenetic Signatures Safeguard the Liver

Avinash Thakur  1 , Pamela A Hoodless  2
Affiliations
Free article
Comment

Repressive Epigenetic Signatures Safeguard the Liver

Avinash Thakur et al. Dev Cell. .
Free article

Abstract

To date, how epigenetic changes are regulated during liver regeneration remains unclear. In this issue of Developmental Cell, Wang and colleagues (2019) employed transcriptomic and epigenomic profiling to explore how Uhrf1, an epigenetic regulator of DNA methylation, functions in liver regeneration using a mouse model of partial hepatectomy.

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  • Epigenetic Compensation Promotes Liver Regeneration.
    Wang S, Zhang C, Hasson D, Desai A, SenBanerjee S, Magnani E, Ukomadu C, Lujambio A, Bernstein E, Sadler KC. Wang S, et al. Dev Cell. 2019 Jul 1;50(1):43-56.e6. doi: 10.1016/j.devcel.2019.05.034. Epub 2019 Jun 20. Dev Cell. 2019. PMID: 31231040 Free PMC article.

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