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Comparative Study
. 1988 Jan;32(1):125-7.
doi: 10.1128/AAC.32.1.125.

Radiometric method for pyrazinamide susceptibility testing of Mycobacterium tuberculosis in egg-yolk-enriched BACTEC 12A medium

C L Woodley  1 , R W Smithwick
Affiliations
Comparative Study

Radiometric method for pyrazinamide susceptibility testing of Mycobacterium tuberculosis in egg-yolk-enriched BACTEC 12A medium

C L Woodley et al. Antimicrob Agents Chemother. 1988 Jan.

Abstract

A radiometric method for testing the susceptibility of Mycobacterium tuberculosis to pyrazinamide in egg-yolk-enriched 12A medium (pH 5.5) is described. We obtained 100% agreement between the 7H10 agar method with 25 microgram of pyrazinamide per ml and the modified radiometric method with a drug concentration of 50 microgram/ml in tests of 90 clinical isolates.

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