Second WIN International Conference on "Integrated approaches and innovative tools for combating insecticide resistance in vectors of arboviruses", October 2018, Singapore

Abstract

The past 40 years have seen a dramatic emergence of epidemic arboviral diseases transmitted primarily by mosquitoes. The frequency and magnitude of the epidemics, especially those transmitted by urban Aedes species, have progressively increased over time, accelerating in the past 10 years. To reduce the burden and threat of vector-borne diseases, the World Health Organization (WHO) has recently adopted the Global Vector Control Response (GVCR) in order to support countries in implementing effective sustainable vector control. The evidence-base to support vector control is however limited for arboviral diseases which make prioritization difficult. Knowledge gaps in the distribution, mechanisms and impact of insecticide resistance on vector control impedes the implementation of locally tailored Aedes control measures. This report summarizes the main outputs of the second international conference of the Worldwide Insecticide resistance Network (WIN) on "Integrated approaches and innovative tools for combating insecticide resistance in arbovirus vectors" held in Singapore, 1-3 October 2018. The aims of the conference were to review progress and achievements made in insecticide resistance surveillance worldwide, and to discuss the potential of integrated vector management and innovative technologies for efficiently controlling arboviral diseases. The conference brought together 150 participants from 26 countries.

Keywords: Arbovirus; Innovative tools; Insecticide resistance; Mosquito; Standardization; Strategic planning; Surveillance; Vector control; WIN network.

Fig. 1

Concept of the population replacement strategy using the wMel strain of Wolbachia (Courtesy of the World Mosquito Programme)

Fig. 2

Concept of the Wolbachia population suppression through cytoplasmic incompatibility (Courtesy of Dr L.C. Ng, NEA, Singapore)

Fig. 3

Management of insecticide resistance in Aedes vectors. Factors contributing to the selection of insecticide resistance in mosquitoes (left panel). Conceptual framework for implementing IRM in Aedes (right panel) (Copyright: Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/). Citation: Dusfour et al. (2019) Management of insecticide resistance in Aedes vectors: advances and challenges. PLoS Negl Trop Dis. 2019 (In Press) [24])

Fig. 4

Conceptual framework of implementing an Integrated Aedes management for the control of Aedes-borne diseases (Copyright: Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/). Citation: Roiz et al. (2018) Integrated Aedes management for the control of Aedes-borne diseases. PLoS Negl Trop Dis. 2018;12:e0006845 [3])

Fig. 5

Gene drive inheritance concept. Gene drives copy themselves onto both chromosomes so the modified chromosome is inherited by all of the offspring (Courtesy of Mr Kyros Kyrou)