Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Feb;42(2):87-90.
doi: 10.1007/BF02556339.

Urinary beta-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone

L Moro  1 , R S Pozzi Mucelli, C Gazzarrini, C Modricky, F Marotti, B de Bernard
Affiliations

Urinary beta-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone

L Moro et al. Calcif Tissue Int. 1988 Feb.

Abstract

beta-1-galactosyl-0-hydroxylysine (GH) was measured in the urine of 59 women and 48 men, aged 30-79 years, by High Performance Liquid Chromatography (HPLC) of the dansylated derivative. Vertebral mineral density, measured by quantitative computed tomography (QCT), and urinary GH were inversely correlated (r = -0.74; P less than 0.001). High rate of bone mineral loss is associated with a high urinary GH excretion. Measurement of GH in urine provides a simple and noninvasive method for the evaluation of the extent of bone resorption in large groups of subjects and appears to be more specific than urinary hydroxyproline excretion.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bone. 1985;6(1):1-7 - PubMed
    1. Methods Enzymol. 1982;82 Pt A:398-410 - PubMed
    1. J Clin Invest. 1970 Aug;49(8):1497-509 - PubMed
    1. J Clin Invest. 1977 May;59(5):819-27 - PubMed
    1. Analyst. 1984 Dec;109(12):1621-2 - PubMed

Publication types

LinkOut - more resources