Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar;130(3):E89-E97.
doi: 10.1002/lary.28163. Epub 2019 Jul 4.

Outcomes of head and neck surgery in patients with a history of solid organ transplantation

Affiliations

Outcomes of head and neck surgery in patients with a history of solid organ transplantation

Zaid Al-Qurayshi et al. Laryngoscope. 2020 Mar.

Abstract

Objectives/hypothesis: Examine the prevalence and outcomes of head and neck surgeries in patients with a history of organ transplantation.

Study design: A retrospective cross-sectional analysis utilizing the Nationwide Readmissions Database, 2010 to 2014.

Methods: The study population included adults patients who underwent head and neck surgeries. Patients with a reported history of solid organ transplantation were compared to patients with no such history.

Results: The study population included 322 transplant patients (76.4% kidney, 8.7% liver, 8.4% heart, 3.0% kidney/pancreas, 2.3% lung, 0.9% kidney/liver, 0.4% pancreas) and 120,401 controls who underwent comparable procedures. Main surgeries that were performed in cases included 37.8% parathyroid, 17.7% thyroid, 11.2% major salivary gland, 10.6% major mouth/tonsil, and 9.6% major nose/paranasal sinuses. Encountering transplant patients in otolaryngology practice has been increasing annually by three patients for every 10,000 procedures performed in the United States. There was no difference in the overall postoperative complications risk (12.5% vs. 10.1%, P = .26); however, cases had a higher risk of acute renal failure (5.4% vs. 1.1%, P < .001) and shock state (0.3% vs. 0.02%, P < .001). Readmission risk was higher for cases (6.8% vs. 3.4%, P = .003). There was no reported in-hospital mortality among cases.

Conclusions: Transplant patients are increasingly encountered in otolaryngology practices. The most common transplanted organ is kidney, and the most commonly performed procedure is parathyroidectomy.

Level of evidence: NA Laryngoscope, 130:E89-E97, 2020.

Keywords: Organ transplantation; head and neck surgery; health services cost; heart; kidney; length of stay; liver; lung; mortality risk; otolaryngology; outcome; pancreas; prevalence.

PubMed Disclaimer

References

BIBLIOGRAPHY

    1. Watson CJ, Dark JH. Organ transplantation: historical perspective and current practice. Br J Anaesth 2012;108(suppl 1):i29-i42.
    1. Schaverien MV, Dean RA, Myers JN, Fang L, Largo RD, Yu P. Outcomes of microvascular flap reconstruction of the head and neck in patients receiving systemic immunosuppressive therapy for organ transplantation. J Surg Oncol 2018;117:1575-1583.
    1. Gourin CG, Terris DJ. Head and neck cancer in transplant recipients. Curr Opin Otolaryngol Head Neck Surg 2004;12:122-126.
    1. Gaya SB, Rees AJ, Lechler RI, Williams G, Mason PD. Malignant disease in patients with long-term renal transplants. Transplantation 1995;59:1705-1709.
    1. Pollard JD, Hanasono MM, Mikulec AA, Le QT, Terris DJ. Head and neck cancer in cardiothoracic transplant recipients. Laryngoscope 2000;110:1257-1261.

Publication types

MeSH terms

LinkOut - more resources