Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2020 Feb;48(2):102-107.
doi: 10.1002/jcu.22752. Epub 2019 Jul 4.

Atrial peak longitudinal strain may be predictive of pancolitis in patients with ulcerative colitis

Muzaffer Kahyaoglu  1 , Nuran Gunay  1 , Emrah Bayam  1 , Yusuf Yilmaz  1 , Cetin Gecmen  2 , Kamil Ozdil  3 , Cihangir Uyan  1
Affiliations
Observational Study

Atrial peak longitudinal strain may be predictive of pancolitis in patients with ulcerative colitis

Muzaffer Kahyaoglu et al. J Clin Ultrasound. 2020 Feb.

Abstract

Background: Ulcerative colitis is a chronic idiopathic inflammatory bowel disease of the colon that is characterized by a relapsing and remitting course. Previous studies have shown that arterial stiffness, carotid intima media thickness, atrial electromechanical delay, and global longitudinal strain suggested subclinical cardiovascular disorders in ulcerative colitis patients. The aims of our study was to evaluate the left atrial function of patients with ulcerative colitis by using speckle tracking echocardiography, and to assess the relationship between echocardiographic variables and the extent of the disease.

Methods: We recruited 51 outpatients with ulcerative colitis in remission phase and 52 healthy volunteers. The ulcerative colitis patients were evaluated by for the extent of the disease by endoscopy at the initial diagnosis.

Results: E/Em , left atrial volume, and left atrial stiffness index were higher, and peak atrial longitudinal strain was lower in pancolitis than in non-pancolitis patients. In the multivariate logistic regression test, peak atrial longitudinal strain and E/Em were found to be independent predictors for pancolitis.

Conclusion: Early detection of myocardial abnormalities by conventional echocardiography and speckle tracking echocardiography, which is a simple and non-invasive technique, may be useful for giving insights to the extent of the disease in ulcerative colitis patients.

Keywords: 2D echocardiography; left atrial strain; ulcerative colitis.

PubMed Disclaimer

References

REFERENCES

    1. Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal world congress of gastroenterology. Can J Gastroenterol. 2005;19:5.
    1. Halling ML, Kjeldsen J, Knudsen T, Nielsen J, Hansen LK. Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases. World J Gastroenterol. 2017;23:6137-6146.
    1. Das KM, Biancone L. Is IBD an autoimmune disorder? Inflamm Bowel Dis. 2008;14:97.
    1. Rellecke P, Strauer BE. Chronic inflammatory bowel disease and cardiovascular complications. Med Klin (Munich). 2006;101:56.
    1. Le Mener S, Huynh-Moynot S, Bronstein JA, et al. Acute myocarditis and inflammatory bowel diseases: a case series of two patients. Rev Med Interne. 2012;33:583.

Publication types

LinkOut - more resources