Hypertension Management in Chronic Kidney Disease and Diabetes: Lessons from the Systolic Blood Pressure Intervention Trial

Abstract

Based on observational and clinical trials, formulation of hypertension guidelines began in 1977. Successive guideline reports recommended lower blood pressure goals, with emphasis shifting to treatment of systolic hypertension. In 2013, responsibility for hypertension guidelines was assigned to the American College of Cardiology and the American Heart Association. The new hypertension guideline was published in 2017, and the Systolic Blood Pressure Intervention Trial (SPRINT) informed many of the recommendations in the new guidelines. This article describes the SPRINT study results and the new guideline recommendations regarding hypertension management and blood pressure goals, with emphasis on chronic kidney disease and diabetes.

Keywords: ACCORD BP; Chronic kidney disease; Diabetes; Guidelines; Hypertension; SPRINT.