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Review
. 2019 Jul-Aug;33(4):1347-1353.
doi: 10.21873/invivo.11610.

Successful Treatment of Anal Canal Cancer Metastasis to the Cranial Bones: A Case Report and Literature Review

Ilaria Benevento  1 , Francesca DE Felice  2 , Nadia Bulzonetti  1 , Rossella Caiazzo  1 , Raffaele Cassese  1 , Daniela Musio  1 , Vincenzo Tombolini  1
Affiliations
Review

Successful Treatment of Anal Canal Cancer Metastasis to the Cranial Bones: A Case Report and Literature Review

Ilaria Benevento et al. In Vivo. 2019 Jul-Aug.

Abstract

Single metastasis to the cranial bone represents a very uncommon occurrence that can arise from an anal canal cancer. No cases of cranial bone metastasis from anal canal carcinoma are available in the literature. Herein, we present a case of a unique metastatic lesion to the right parietal bone that occurred after curative chemoradiotherapy of primary squamous cell anal canal carcinoma. The patient received radiotherapy and systemic platinum-based chemotherapy, with optimal local control, high compliance and a well tolerable level of toxicity.

Keywords: Anal canal carcinoma; bone metastasis; calvarial; chemotherapy; hypofractionated; radiotherapy; survival.

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Conflict of interest statement

All Authors declare no conflicts of interest regarding this study.

Figures

Figure 1
Figure 1. Computed tomography images of the right parietal bone metastasis before (left) and after (right) local radiation therapy.
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References

    1. Kakhki VR, Anvari K, Sadeghi R, Mahmoudian AS, Torabian M Kakhki. Pattern and distribution of bone metastases in common malignant tumors. Nucl Med Rev Cent East Eur. 2013;16(2):66–69. PMID: 24068635. DOI: 10.5603/NMR. 2013.0037. - PubMed
    1. Ozgiray E, Perumal K, Cinar C, Caliskan Ke, Ertan Y, Yurtseven, Oktar N, Ovul I, Oner Management of calvarial tumors: a retrospective analysis and literature review. Turk Neurosurg. 2016;26:690–698. PMID: 27337230. DOI: 10.5137/ 1019-5149.JTN.12537-15.0. - PubMed
    1. Constans JP, Donzelli R. Surgical features of cranial metastases. Surg Neurol. 1981;15(1):35–38. PMID: 7256522. - PubMed
    1. Nagamine Y, Suzuki J, Katakura R, Yoshimoto T, Matoba N, Takaya K. Skull metastasis of thyroid carcinoma. Study of 12 cases. J Neurosurg. 1985;63(4):526–531. PMID: 4032016. DOI: 10.3171/jns.1985.63.4.0526. - PubMed
    1. Anegawa S, Hirohata S, Tokutomi T, Kuramoto S. Spontaneous epidural hematoma secondary to dural metastasis from an ovarian carcinoma – case report. Neurol Med Chir (Tokyo) 1989;29(9):854–856. PMID: 2480548. - PubMed

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