Evidence of human infection with a rat-associated Hantavirus in Baltimore, Maryland
- PMID: 3128102
- DOI: 10.1093/oxfordjournals.aje.a114871
Evidence of human infection with a rat-associated Hantavirus in Baltimore, Maryland
Abstract
Human sera obtained from two sources in Baltimore were tested for antibodies against a Hantavirus by a variety of techniques. Four persons out of 1,788 had hantaviral antibody as demonstrated by immunofluorescent assay, enzyme-linked immunosorbent assay, and neutralizing assay. Neutralizing antibody titrations against three test viruses indicated that infections were caused by a rat-associated virus. Medical histories of two subjects indicated life-long residence in Baltimore and an absence of foreign travel, implicating a local source of infection.
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