Reassessment of c-Kit⁺ Cells for Cardiomyocyte Contribution in Adult Heart

Lingjuan He^{1

2}, Maoying Han^{2

3}, Zhenqian Zhang², Yan Li², Xiuzhen Huang², Xiuxiu Liu², Wenjuan Pu², Huan Zhao², Qing-Dong Wang⁴, Yu Nie⁵, Bin Zhou^{2

3

6

7

8}

Affiliations

¹ The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, China (L.H.).
² State Key Laboratory of Cell Biology, Chinese Academy of Sciences Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, China (L.H., M.H., Z.Z., Y.L., X.H., X.L., W.P., H.Z., B.Z.).
³ ShanghaiTech University, China (M.H., B.Z.).
⁴ Bioscience Heart Failure, Cardiovascular, Renal, and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (Q.-D.W.).
⁵ State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.N.).
⁶ Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China (B.Z.).
⁷ Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China (B.Z.).
⁸ Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, China (B.Z.).

Lingjuan He et al. Circulation. 2019.

. 2019 Jul 9;140(2):164-166.

doi: 10.1161/CIRCULATIONAHA.119.039909. Epub 2019 Jul 8.

Lingjuan He^{1

2}, Maoying Han^{2

3}, Zhenqian Zhang², Yan Li², Xiuzhen Huang², Xiuxiu Liu², Wenjuan Pu², Huan Zhao², Qing-Dong Wang⁴, Yu Nie⁵, Bin Zhou^{2

3

6

7

8}

¹ The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, China (L.H.).
² State Key Laboratory of Cell Biology, Chinese Academy of Sciences Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, China (L.H., M.H., Z.Z., Y.L., X.H., X.L., W.P., H.Z., B.Z.).
³ ShanghaiTech University, China (M.H., B.Z.).
⁴ Bioscience Heart Failure, Cardiovascular, Renal, and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (Q.-D.W.).
⁵ State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.N.).
⁶ Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China (B.Z.).
⁷ Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China (B.Z.).
⁸ Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, China (B.Z.).

No abstract available

Keywords: c-Kit+ cells; cardiomyocytes; dual recombinase; genetic lineage tracing.

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