Duration of Antibiotic Therapy: Shorter Is Better

Affiliations

¹ Los Angeles County-University of Southern California Medical Center, Los Angeles, California (B.S.).
² Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island (L.B.R.).

Editorial

Brad Spellberg et al. Ann Intern Med. 2019.

. 2019 Aug 6;171(3):210-211.

doi: 10.7326/M19-1509. Epub 2019 Jul 9.

¹ Los Angeles County-University of Southern California Medical Center, Los Angeles, California (B.S.).
² Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island (L.B.R.).

No abstract available

Conflict of interest statement

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M19-1509.

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study.
Vaughn VM, Flanders SA, Snyder A, Conlon A, Rogers MAM, Malani AN, McLaughlin E, Bloemers S, Srinivasan A, Nagel J, Kaatz S, Osterholzer D, Thyagarajan R, Hsaiky L, Chopra V, Gandhi TN. Vaughn VM, et al. Ann Intern Med. 2019 Aug 6;171(3):153-163. doi: 10.7326/M18-3640. Epub 2019 Jul 9. Ann Intern Med. 2019. PMID: 31284301

1. Rice LB. The Maxwell Finland Lecture: For the duration–rational antibiotic administration in an era of antimicrobial resistance and Clostridium difficile. Clin Infect Dis. 2008;46:491–6. doi:10.1086/526535 - DOI - PubMed
1. Spellberg B The new antibiotic mantra–“shorter is better”. JAMA Intern Med. 2016;176:1254–5. doi:10.1001/jamainternmed.2016.3646 - DOI - PMC - PubMed
1. Wald-Dickler N, Spellberg B. Short course antibiotic therapy–replacing Constantine units with “shorter is better”. Clin Infect Dis. 2019. doi:10.1093/cid/ciy1134 - DOI - PMC - PubMed
1. Gjika E, Beaulieu JY, Vakalopoulos K, et al. Two weeks versus four weeks of antibiotic therapy after surgical drainage for native joint bacterial arthritis: a prospective, randomised, non-inferiority trial. Ann Rheum Dis. 2019. doi:10.1136/annrheumdis-2019-215116 - DOI - PMC - PubMed
1. Royer S, DeMerle KM, Dickson RP, et al. Shorter versus longer courses of antibiotics for infection in hospitalized patients: a systematic review and meta-analysis. J Hosp Med. 2018;13:336–42. doi:10.12788/jhm.2905 - DOI - PMC - PubMed