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Case Reports
. 1988 Jan;21(1):113-5.
doi: 10.1093/jac/21.1.113.

Enterococcal superinfection in patients treated with ciprofloxacin

M J Zervos  1 , A E Bacon 3rd, J E Patterson, D R Schaberg, C A Kauffman
Affiliations
Case Reports

Enterococcal superinfection in patients treated with ciprofloxacin

M J Zervos et al. J Antimicrob Chemother. 1988 Jan.

Abstract

Two patients developed serious enterococcal superinfection following therapy with intravenous ciprofloxacin. The strains causing bacteraemia were susceptible to low concentrations of ciprofloxacin when tested at a standard inoculum. However, at an inoculum of 1 X 10(7) cfu/ml they were resistant to high concentrations of ciprofloxacin. Our data suggest that ciprofloxacin should not be used to treat patients with serious enterococcal infection and that patients treated with ciprofloxacin should be monitored carefully for the development of enterococcal superinfection.

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