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Review
. 2019 Jun 27;5(6):FSO395.
doi: 10.2144/fsoa-2018-0127.

Accurate identification of clinically important Acinetobacter spp.: an update

Saranya Vijayakumar  1 , Indranil Biswas  2 , Balaji Veeraraghavan  1
Affiliations
Review

Accurate identification of clinically important Acinetobacter spp.: an update

Saranya Vijayakumar et al. Future Sci OA. .

Abstract

Acinetobacter species have emerged as one of the most clinically important pathogens. The phenotypic techniques which are currently available are insufficient in accurately identifying and differentiating the closely related and clinically important Acinetobacter species. Here, we discuss the advantages and limitations of the conventional phenotypic methods, automated identification systems, molecular methods and MALDI-TOF in the precise identification and differentiation of Acinetobacter species. More specifically, several species of this genus are increasingly reported to be of high clinical importance. Molecular characterization such as of bla OXA-51-like PCR together with rpoB sequencing has high discriminatory power over the conventional methods for Acinetobacter species identification, especially within the Acinetobacter calcoaceticus-Acinetobacter baumannii complex.

Keywords: ACB complex; Acinetobacter baumannii; MALDI-TOF; matrix-assisted laser desorption ionization-time of flight mass spectrometry; molecular methods; phenotypic methods.

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Conflict of interest statement

Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.

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